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Sequence Manipulation Suite
Pairwise Align Protein
Pairwise Align Protein accepts two protein sequences and determines the optimal global alignment. Use Pairwise Align Protein to look for conserved sequence regions.
Paste sequence one (in raw sequence or FASTA format) into the text area below. Input limit is 2000 characters.
>Human p53 SSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPV QLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQH LIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCM GGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENL
Paste sequence two (in raw sequence or FASTA format) into the text area below. Input limit is 2000 characters.
>Xenopus p53 SCAVPSTDDYAGKYGLQLDFQQNGTAKSVTCTYSPELNKLFCQLAKTCPL LVRVESPPPRGSILRATAVYKKSEHVAEVVKRCPHHERSVEPGEDAAPPS HLMRVEGNLQAYYMEDVNSGRHSVCVPYEGPQVGTECTTVLYNYMCNSSC MGGMNRRPILTIITLETPQGLLLGRRCFEVRVCACPGRDRRTEEDNY
Use the following parameters to specify how alignments are scored.
Scoring matrix
PAM30
PAM70
BLOSUM80
BLOSUM62
BLOSUM45
Value for gaps preceding a sequence
6
5
4
3
2
1
0
-1
-2
-3
-4
-5
-6
Value for internal gaps
6
5
4
3
2
1
0
-1
-2
-3
-4
-5
-6
Value for gaps following a sequence
6
5
4
3
2
1
0
-1
-2
-3
-4
-5
-6
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